Our BRCA and family history clinic at 35 Weymouth Street, London W1G 8BJ, assesses inherited breast cancer risk and, where appropriate, offers risk-reducing breast surgery and reconstruction. Care is consultant-led by Mr Debashis Ghosh, Consultant Breast & Oncoplastic Surgeon (GMC 4657664). We accept both self-pay and insured patients (insurer fees honoured as per policy cover).
For women with a significantly elevated genetic risk of developing breast cancer, risk-reducing breast surgery can be a proactive step in significantly lowering that risk.
This procedure typically involves removing both breasts (bilateral mastectomy) and, in many cases, reconstructing new breasts with implants or tissue from your own body.
Risk-reducing surgery can reduce the likelihood of developing breast cancer by up to 90–95%, making it an important consideration for women with certain risk factors. You may be a candidate for risk-reducing breast surgery if:
Registered & Regulated for practice in the United Kingdom
We use validated risk assessment models, such as Tyrer-Cuzick and Manchester scoring, alongside your family history to calculate your individual lifetime risk of developing breast cancer.
Before any testing takes place, our specialist genetic counsellors talk you through what a positive or negative result could mean, helping you make an informed, unpressured decision.
We offer testing for BRCA1, BRCA2, PALB2 and other cancer-associated gene mutations, giving you clear, accurate information to guide your risk-reducing options.
This involves the removal of the entire breast, including the nipple and areola, while leaving the underarm lymph nodes intact. It offers significant cancer risk reduction for high-risk patients.
This surgery preserves the outer skin of the breast whilst removing the tissue inside. It is ideal for those planning breast reconstruction for more natural post surgical results.
In this approach, the breast tissue is removed while leaving the nipple and areola intact which can provide more aesthetic outcomes, especially when combined with breast reconstruction.
Reconstruction can be done with implants or using your own tissue and is often performed during or after risk-reducing surgery to restore the breast's appearance. Your risk-reducing mastectomy and reconstruction are performed by the same surgeon, ensuring seamless, continuous care — learn more on our Breast Reconstruction page.
Led by a dual European Board-certified consultant (FEBS in Breast Surgery and Surgical Oncology), formerly Clinical Director of Breast Services for NHS England’s NCL Cancer Alliance, working alongside a multidisciplinary team of radiologists and oncologists.
Our clinics use advanced technologies and techniques, including intra-operative testing, to support accurate diagnosis and effective treatment.
Our dedicated breast care nursing team offer emotional and practical support, guiding you through each step of your diagnosis and treatment with compassion and expertise.
You are seen by Mr Debashis Ghosh, Founder and Lead Surgeon of Harley Street Breast Care, not passed between junior clinicians. He is a GMC-registered Consultant Breast & Oncoplastic Surgeon (GMC 4657664) with dual European Board certification in Breast Surgery and Surgical Oncology, and has been a consultant since 2012.
Treatment planning has multidisciplinary input from radiologists, oncologists and pathologists. Read Mr Debashis Ghosh’s full profile.
Risk-reducing surgery lowers the risk of breast cancer significantly but does not remove it entirely, so your specialist will advise on monitoring afterwards. If you would rather start with surveillance, see our breast cancer screening service.
From verified Doctify reviews: “The care was always respectful and never patronizing.” · “The team was honest, realistic, and always had my best interest at heart.” · “Every step and option was explained in a clear and comforting way.”
No GP referral is required for a private consultation. If you are using private medical insurance, check your insurer’s requirements before you book.
Yes. A strong family history of breast cancer is a reason to be assessed. Your lifetime risk is estimated with validated models and your family history, and genetic counselling and testing are discussed with you where appropriate.
Reconstruction is often performed during or after risk-reducing surgery, using implants or your own tissue. Which approach suits you is decided with your surgeon.
Yes. A second opinion is a normal and accepted part of cancer care – see our Trusted Second Opinion service.
Genetic risk reduction helps individuals with a family history of breast cancer or inherited genetic mutations (like BRCA1 and BRCA2) manage and lower their breast cancer risk. It includes options like enhanced screening, preventive surgeries, and personalised lifestyle advice to protect against breast cancer.
Genetic risk reduction is ideal for those with a strong family history of breast cancer, known genetic mutations such as BRCA, or specific risk factors. A consultation with a genetic counselor can help determine if you’re at high risk and need these services.
Mutations in BRCA1 and BRCA2 genes can significantly raise the risk of breast cancer and ovarian cancer by impairing the body’s DNA repair system, leading to higher chances of cancer development. Genetic risk reduction strategies can help manage these risks.
Risk reduction options include frequent screenings, preventive medications, and surgeries like prophylactic mastectomy. The best choice depends on your genetic test results, family history, and individual risk factors.
A prophylactic mastectomy involves removing one or both breasts to lower the risk of breast cancer, especially for those with BRCA mutations. While it can significantly reduce the risk, it does not eliminate it entirely, making regular monitoring still important.
We see both self-pay and privately insured patients, and insurer fees are honoured as per policy cover. Whether your policy covers genetic testing or risk-reducing surgery depends on your insurer and your cover, so check with your insurance company before your appointment.
Genetic counseling involves reviewing your family history, understanding genetic testing, and discussing the best preventive steps if you’re high-risk. Counselors guide you through your options and the benefits and limitations of each.
Genetic testing typically involves a blood or saliva sample to detect mutations in genes like BRCA1 and BRCA2, which increase breast cancer risk. Test results can guide your doctor in creating a personalised risk reduction plan.
Yes, making lifestyle changes like maintaining a healthy weight, reducing alcohol, exercising, and avoiding smoking can lower breast cancer risk. These changes work alongside genetic risk reduction strategies to improve your overall health.
People at high risk for breast cancer may need annual screenings, like mammograms or MRIs, starting at a younger age. Your doctor will customise a screening schedule to monitor for early signs of cancer.
Preventive mastectomy has potential risks, including infection, bleeding, and physical or emotional changes. It’s a personal decision, and your healthcare team will guide you through all considerations.
High-risk individuals can access genetic counseling, mental health resources, and support groups to help manage the physical and emotional aspects of risk reduction. Support networks provide valuable guidance and connect you with others in similar situations.
